The Colts won at least 12 games for the fourth consecutive season. They also won the AFC South Division Championship for the fourth time in a row, and won the American Football Conference Championship title against the New England Patriots on January 21, 2007 by a score of 38–34 to advance to Super Bowl XLI and play against the Chicago Bears. Indianapolis defeated the Chicago Bears 29–17 on February 4, 2007 at Dolphin Stadium to win the franchise's first Super Bowl since Super Bowl V in 1970, and first since relocating to Indianapolis. It was their 4th world championship ever (1958, 1959, 1970, and 2006.)
The 2006 Colts surrendered 5.33 rushing yards-per-attempt, by far the worst since the merger, and seventh-worst in NFL history. Still, the Colts managed to win a championship with the help of the most statistically efficient offense in the league.