The game took place on Sunday, November 25, 2012, at Rogers Centre in Toronto, Ontario. This was the fourth Grey Cup game played at Rogers Centre, and the 46th in the city of Toronto.
The Argonauts defeated the Stampeders 35–22 to win their sixteenth Grey Cup title.
This was the third meeting between Calgary and Toronto for the Grey Cup championship and the first since the 79th Grey Cup in 1991. This was also the second consecutive year that the Grey Cup game involved, and was won by, the team from the host city. The result of the game also meant that Argonauts owner David Braley became the first team owner to win back-to-back Grey Cups with two different teams; Braley also owns the 2011 champions, the BC Lions. Over 5.8 million viewers watched the game, with roughly 5.5 million originating from English Canada, making the game the most-watched Grey Cup ever recorded on English-language television.
Following the game, Toronto running back Chad Kackert was named the Most Valuable Player. His teammate, defensive end Ricky Foley received the Dick Suderman Trophy as the Most Valuable Canadian.