The 2000 Oklahoma Sooners football team represented the University of Oklahoma in the 2000 college football season, the 106th season of Sooner football. The team was led by Bob Stoops in his second season as the OU head coach. They played their home games at Gaylord Family Oklahoma Memorial Stadium in Norman, Oklahoma. They were a charter member of the Big 12 conference.
The Sooners opened the season ranked number 19, the first time they had made it into a pre-season poll in five years. Conference play began with a win over Kansas at home on September 30, and ended with a win over the Kansas State Wildcats in the Big 12 Championship Game on December 2.
The Sooners finished the season 13-0 (9-0 in Big 12), their most wins in school history, while winning their first Big 12 title and their 37th conference title overall. They were invited to the 2001 Orange Bowl, which served as the BCS National Championship Game that year, where they beat Florida State, 13-2. This is Oklahoma's 7th claimed and most recent national championship.
Following the season, Torrance Marshall was selected in the 3rd round of the 2001 NFL Draft, along with Josh Heupel in the 6th. Tying with the 1999 and 2001 seasons, this is the least amount of Sooners drafted in the 15 years of the Stoops era, with only two players from Oklahoma selected.